V─Бta┼Ыonita is the disease produced by vitiated v─Бta do┼Ыa and rakta which impede the gati of each other causing the disease.
This disease is also renamed as ─Бdhyaroga i.e. mainly affluent people are affected by the disease as said by Chakrap─Бni.
Very detailed aetiological factors had been mentioned in Caraka Samhita which were in practice during that very time and now has become either out dated or localized to very remote places in India, like pinyaka (in ancient time, the residue of oil seeds were eaten after oil had been extracted), madya like arn─Бl, sauvir, sukta, sur─Б, ─Бsava like alcoholic beverages which were in use which have been replaced by refine alcoholic drinks like beer, wine etc. Again during old time horse, camel and y─Бna (carts) were used for travelling which may be co related with travelling means of modern era.
The disease is predominant among the people who in general are not habitual to physical activity rather they have more sedentary lifestyle. People of pitta prakriti (pitta constitution) are prone to develop v─Бta┼Ыonita, sukum─Бratwa (delicate personality) is the characteristic feature of pitta prakriti.
Each of the three do┼Ыa, which are physiological entity can be subdivided into three types depending on the mode of action which each of the three execute in the normal and pathological stages,
a) normal physiological activities of the body are dh─Бtu do┼Ыa (normal do┼Ыa),
b) abnormal physiological activities of do┼Ыa in the body- (vitiated do┼Ыa) and
c) by products of abnormal physiology will be the mala do┼Ыa (waste product) only which have anatomical entity and are removable from the body.
All normal micro and macro movemental activities in the body are dh─Бtuv─Бta, all the activities responsible for heat production and regulation are dh─Бtu pitta and all the synthesis or productive activities of the body are dh─Бtu kapha. Do┼Ыa (normal physiological activities) are very essential for the body so in that context they are called as dh─Бtu, but when they are prone to vitiation they are called as do┼Ыa. All abnormal movemental (macro and micro) activities in the body are caused by vitiated v─Бta do┼Ыa, abnormality in heat production and regulation in the body are caused by vitiated pitta do┼Ыa and abnormal synthesis in the body are caused by vitiated kapha do┼Ыa and by products of abnormal activities (pathological activities) are mala do┼Ыa, they tarnish (malini karnat) the body so called mala.
In case of v─Бta ┼Ыonita there should be abnormality in movemental activity (v─Бta do┼Ыa) as well as abnormality of rakta. Due to metabolic disturbances (dh─Бtw─Бgni vaishamya) there is overproduction of metabolites like uric acid, calcium pyrophosphate, etc. High concentration of these metabolites in blood should be considered as raktadu┼Ыti, high concentration of uric acid and other metabolites in blood slows the propulgation of blood in capillaries and hence there is stagnation of it near the joints and dependent parts of the body. Uric acid escapes and enters into the joints and other tissues from the stagnated hyperuricemic blood, and the same time there may be reduced excretion of uric acid through kidneys, these all disturbed movemental activities are considered as v─Бta du┼Ыti and over production of uric acid during metabolism of nucleoproteins and through de novo pathway may be considered as agnidu┼Ыti. It is observed that patients suffering from v─Бta┼Ыonita also have visam─Бgni (disturbed digestive capability), it is a rule that if the jathar─Бgni (digestive capability) is disturbed the other types of agn─л (metabolism) will also be disturbed. It is the beauty of Ayurvedic science that has mentioned all and very different etiological factors responsible for a) agni vaisamya b) do┼Ыa prakopa and c) dh─Бtu dushti directly or indirectly.
Inflammation of joints may also occur by some other metabolites like calcium pyrophosphate crystal deposition which is also a by product and resultant of agni dushti (disturbed metabolism).
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Prof. Satyendra Narayan Ojha
MD PhD (Kayachikitsa)
Director
Yashwant Ayurveda College & P.G. Training & Research Center
Mobile No. +91 9822177155
email: drsnojha@rediffmail.com
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